Referenze Scientifiche

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Spirulina

Haematococcus pluvialis (Astaxantina)

Nishida, Y., Berg, P. C., Shakersain, B., Hecht, K., Takikawa, A., Tao, R., Kakuta, Y., Uragami, C., Hashimoto, H., Misawa, N., et al. (2023). Astaxanthin: Past, Present, and Future. Mar. Drugs, 21(10), 514.
Ambati, R. R., Moi, P. S., Ravi, S., & Aswathanarayana, R. G. (2014). Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review.
Park, J. S., Chew, B. P., Choi, J. H., Kim, Y. K., & Lim, L. L. (2010). Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutrition & Metabolism, 7(1), 18.
Stachowiak, B., & Szulc, P. (2021). Astaxanthin for the Food Industry. Molecules, 26(9), 2666.
Fassett, R. G., & Coombes, J. S. (2012). Astaxanthin in Cardiovascular Health and Disease. Molecules, 17(2), 2037-2048.
Grimmig, B., Daly, L., Subbarayan, M., Hudson, C., Williamson, R., Nash, K., & Bickford, P. C. (2018). Astaxanthin Is Neuroprotective in an Aged Mouse Model of Parkinson’s Disease. Oncotarget, 9(7), 10388–10401.
Nieman, D. C., Woo, J., Sakaguchi, C. A., Omar, A. M., Tang, Y., Davis, K., Pecorelli, A., Valacchi, G., & Zhang, Q. (2023). Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins. Journal of the International Society of Sports Nutrition, 20(1), 2220225.
Ooi, L. K., Ham, D. J., Kamada, H., & Suzuki, K. (2021). Benefits of Exercise and Astaxanthin Supplementation: Are There Additive or Synergistic Effects? Nutrients, 13(6), 1907.
Ishiwata, S., Kato, T., Kasai, T., Sato, A., Yatsu, S., Matsumoto, H., Shitara, J., Murata, A., Shimizu, M., Suda, S., Matsue, Y., Naito, R., Hiki, M., & Daida, H. (2021). Changes in self-reported physical activity and health-related quality of life following 3-month astaxanthin supplementation in patients with heart failure: results from a pilot study. Annals of Palliative Medicine, 10(2), 1396-1403.
Hasani, M., Saeedi, A., & Khodabakhshi, A. (2024). Effect of astaxanthin on physical activity factors, lipid profile, inflammatory markers, and muscle damage indices in healthy young men: A systematic review and meta-analysis. Journal of Functional Foods, 122, 106477.
Baralic, J., Andjelkovic, M., Djordjevic, E., Dikic, N., Radivojevic, D., Stojanovic, G., Blagojevic, V., Djordjevic, V., & Milanovic, Z. (2015). Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Muscle Soreness after Exercise in Elite Male Soccer Players. Evidence-Based Complementary and Alternative Medicine, 2015, 783761.
Othman, S. N. H., Thilagan, J. S., Ming, P., Aliasak, R., Islam, R., & Hoque, N. (2021). Haematococcus pluvialis as a Potential Source of Astaxanthin with Diverse Applications in Industrial Sectors—Current Research and Future Directions.
Zhao, Y., Zhang, Y., Wang, Y., Chen, H., Cai, X., Booth, J. S., Dohm, G. L., & Yang, X. (2019). High-Dose Astaxanthin Supplementation Suppresses Antioxidant Enzyme Activity during Moderate-Intensity Swimming Training in Mice. Oxidative Medicine and Cellular Longevity, 2019, 9041929.
Honda, M., & Nishida, Y. (2023). In Vitro Evaluation of Skin-Related Physicochemical Properties and Biological Activities of Astaxanthin Isomers. Cosmetics, 10(4), 94.
Valenzuela, S., Castro, M., Medina-Egea, A., Sánchez-Zurano, A., Acién-Fernández, G., & Lafarga, T. (2021). Microalgae Derived Astaxanthin Research and Consumer Trends and Industrial Use as Food. Foods, 10(10), 2303.
Morilla, M. J., Ghosal, K., & Romero, E. L. (2023). More Than Pigments: The Potential of Astaxanthin and Bacterioruberin-Based Nanomedicines. Pharmaceutics, 15(7), 1828.
Galasso, C., Orefice, I., Pellone, P., Cirino, P., Miele, R., Ianora, A., Brunet, C., & Sansone, C. (2018). On the Neuroprotective Role of Astaxanthin: New Perspectives? Marine Drugs, 16(8), 247.
Tominaga, K., Hongo, N., Fujishita, M., Takahashi, Y., & Adachi, Y. (2017). Protective effects of astaxanthin on skin deterioration. Journal of Clinical Biochemistry and Nutrition, 61(3), 237–244.
Zeng, X., Chen, Q., & Ou, C. (2021). Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing. Nutrients, 13(11), 3793.
Bjørklund, G., Gasmi, A., Lenchyk, L., Shanaida, M., Zafar, S., Mujawdiya, P. K., Lysiuk, R., Antonyak, H., Noor, S., Akram, M., Saeed, K., Pirzada, S., Ukkuru, T., & Parvez, M. (2022). The Role of Astaxanthin as a Nutraceutical in Health and Age-Related Conditions. Molecules, 27(21), 7167.
Kusak, N., Rudziński, G., Pażyra, A., Żak, N., Jaworska, B., & Stanicki, P. (2024). The effects of antioxidants on various body systems and physical activity - a literature review on Astaxanthin. Quality in Sport, 23(1), 54626.
Nakagawa, K., Kudo, A., Yamashita, K., Aoi, H., & Osawa, N. (2011). Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. British Journal of Nutrition, 105(11), 1563–1571.

Chlorella

Barghchi, H., Dehnavi, Z., Nattagh-Eshtivani, E., Alwaily, E. R., Almulla, A. F., Kareem, A. K., Barati, M., Ranjbar, G., Mohammadzadeh, A., Rahimi, P., & Pahlavani, N. (2023). The effects of Chlorella vulgaris on cardiovascular risk factors: A comprehensive review on putative molecular mechanisms. Biomedicine & Pharmacotherapy, 162, 114624.
Wu H, Yang P, Li A, Jin X, Zhang Z, Lv H. Chlorella sp.-ameliorated undesirable microenvironment promotes diabetic wound healing. Acta Pharm Sin B. 2023 Jan;13(1):410-424. doi: 10.1016/j.apsb.2022.06.012. Epub 2022 Jun 23. PMID: 36815029; PMCID: PMC9939294.
Safi, C., Zebib, B., Merah, O., Pontalier, P.-Y., & Vaca-Garcia, C. (2014). Morphology, composition, production, processing and applications of Chlorella vulgaris: A review. Renewable and Sustainable Energy Reviews, 35, 265-278.
Liu J, Chen F. Biology and Industrial Applications of Chlorella: Advances and Prospects. Adv Biochem Eng Biotechnol. 2016;153:1-35. doi: 10.1007/10_2014_286. PMID: 25537445.
Sun Z, Li T, Zhou ZG, Jiang Y. Microalgae as a source of lutein: chemistry, biosynthesis, and carotenogenesis. Adv Biochem Eng Biotechnol. 2016;153:37-58. doi: 10.1007/10_2015_331. PMID: 26475466.
Bernard O, Mairet F, Chachuat B. Modelling of Microalgae Culture Systems with Applications to Control and Optimization. Adv Biochem Eng Biotechnol. 2016;153:59-87. doi: 10.1007/10_2014_287. PMID: 25604163.
Havlik I, Scheper T, Reardon KF. Monitoring of Microalgal Processes. Adv Biochem Eng Biotechnol. 2016;153:89-142. doi: 10.1007/10_2015_328. PMID: 26289537.
Zheng, X., Liu, Y., Cheng, K., Liu, Z., Li, S., Yang, Z., Zhou, Y., Liu, B., & Hao, J. (2024). Application and prospect of microbial food Chlorella. Heliyon, 10(10), e37025.
Bito, T.; Okumura, E.; Fujishima, M.; Watanabe, F. Potential of Chlorella as a Dietary Supplement to Promote Human Health. Nutrients 2020, 12, 2524. https://doi.org/10.3390/nu12092524
An, J. H., Boo, K. S., Kim, K. E., Kim, H. Y., Kim, S. H., & Lee, K. W. (2016). Dietary supplementation of Chlorella vulgaris improves broiler chicken growth performance and meat quality. SpringerPlus, 5(1), 718.
Sherafati, N., Vakili, M. B., Beigrezaei, M., Asadi, M., & Sadeghi, O. (2022). The effect of Chlorella vulgaris supplementation on lipid profile in adults: A systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 66, 102822.
Rao, A. R., & Sibi, G. (2021). An efficient method for the sequential production of lipid, lutein and its geometrical isomers from Chlorella vulgaris biomass. Journal of Applied Phycology, 33(1), 605-615.